Since Kv1.3 channels are expressed in the CNS and immune cells, including microglia, dendritic cells, T (TEM cells), B lymphocytes, and macrophages [32], they mediate autoimmune diseases [33], participate in chronic inflammatory diseases and cancer progression (due to its double role in proliferation and apoptosis regulation) [34]. The gene discussed is KCNA3; the disease is autoimmune disease.