Familial hypercholesterolemia (FH) is the most common monogenic autosomal dominant disorder caused by genetic alterations in the low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB) or proprotein convertase subtilisin/kexin type 9 (PCSK9) genes. This evidence concerns the gene LDLR and familial hyperaldosteronism.