Moreover, hypertension was not detected as a risk factor in our study, which is different from previous studies.[22] Several studies have reported that angiotensin-converting enzyme 2 (ACE2) plays a role as a gateway for SARS-CoV-2 and other coronaviruses,[23] and ACE inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) have been speculated to increase damage to the lung, which might enhance expression of ACE2 and help SARS-CoV-2 enter the host cell.[24] However, to date, no research has proven this hypothesis. The gene discussed is ACE; the disease is hypertensive disorder.