HTT and neurodegenerative disease: In neurodegenerative diseases (ND), FOXO factors such as DAF‐16 and FOXO3 may protect against the cytotoxicity of Huntingtin (HTT) (Parker et al., 2012; Tourette et al., 2014), SOD1 and p150Glued (Mojsilovic‐Petrovic et al., 2009), α‐synuclein (Pino et al., 2014), and Aß (Cohen et al., 2009).