CRS is characterized by excessive activation of lymphocytes, dendritic cells and macrophages, as well as other compounds playing significant roles in immune response, Excessive stimulation of immune response results in the redundant release of inflammatory cytokines, including IFN-γ, and IFN-α, Il-1, IL-5, IL-6, IL-8, IL-10, IL-12, tumour necrosis factor α, monocyte chemotactic protein 1, macrophage inflammatory protein and GM-CSF (Maude et al. 2014). Here, IL6 is linked to congenital rubella syndrome.