Research conducted by Kunnimalaiyaan et al.168has demonstrated that LY2090314 (a GSK‐3 inhibitor) is capable for causing growth inhibition and inducing apoptosis in NB cells, and also reducing the survivin level. Withanolides (WA, WGA, WGB‐DA, WGA‐TA) have also been found to be cytotoxic to NB cells, potentially because they downregulate survivin in NB cells.169. This evidence concerns the gene BIRC5 and neuroblastoma.