PTEN and cancer: The protein data including 32 kinds of cancers from TCGA (listed in Table S2) were collected for analysis, showing general positive correlations between BAP1 and PTEN in 17 of them, including esophageal carcinoma (ESCA), kidney chromophobe (KICH), bladder urothelial carcinoma (BLCA), and prostate adenocarcinoma (PRAD), whereas slight negative correlations only in brain lower grade glioma (LGG) and testicular germ cell tumors (TGCT) (Fig. 7F,G).