Also tested on prostate cancer cells (this time of the PC-3 cell line), a luminescent Pd(II) complex, [Pd(L)Cl], with acyclic tridentate ligand quinoline-2-carboxaldehyde-2-pyridylhydrazone, also revealed caspase-3 activation as indicative of cell apoptosis (20). The gene discussed is CASP3; the disease is Familial prostate cancer.