H. Dean et al. conducted genetic analysis of 20 single nucleotide polymorphisms (SNPs) in IL-10 and TNF/LTA loci in three independent case-control studies (2,635 cases and 4,234 controls), discovered IL-10 rs1800896 was related to DLBCL, as well as T-cell lymphoma (29). This evidence concerns the gene TNF and diffuse large B-cell lymphoma.