In addition to IL-10, IFN γ, IL-8, IL-17, IL-23, monocyte chemoattractant protein-1 and macrophage inflammatory protein-1β, and RANTES negatively also have negative effects on clinical prognosis in patients with ALK- anaplastic large cell lymphoma (27). This evidence concerns the gene CXCL8 and anaplastic large cell lymphoma.