A previous study investigating OS by paraprotein class found that myeloma patients with IgG had the longest overall survival (median: 2.5 years; 95% CI: 2.3–2.7), followed by IgA (median: 2.3 years; 95% CI: 2.1–2.6) and light chain–only paraprotein (median: 1.9 years; 95% CI: 1.5–2.3) (24). Here, TNFSF14 is linked to plasma cell myeloma.