Examples of intracellular molecules sorted by G1 and/or G2 included kinases (Casein kinases, CdK5), phosphatases (Ppp3r1), rho GTPase-related proteins (Cdc42, Arhgap1), molecular motors (dyneins and kinesins), cytoskeletal associated proteins (myosins, Tau, Arp, septins), proteins involved in exocytosis/endocytosis processes (exocyst components, Snap25, Clta, Ap2, Picalm-1), as well as proteins involved in neurodegenerative pathologies such as AD (Tau, Picalm-1). The gene discussed is CDK5; the disease is Alzheimer disease.