In the total study population, this analysis revealed that age (≥ 75 years) (odds ratio [OR]: 2.12; 95% confidence interval [CI] 1.20–3.75), obesity (OR: 0.15; 95% CI 0.07–0.32), hypertension (OR: 0.44; 95% CI 0.25–0.76), certification of long-term care (OR: 3.32; 95% CI 1.41–7.81), the number of daily conversations (with < 5 persons) (OR: 0.44; 95% CI 0.25–0.77) and malnutrition (total cholesterol < 150 mg/dl and/or albumin < 3.5 g/dl) (OR: 2.42; 95% CI 1.04–5.60) were all independent predictors of sarcopenia. This evidence concerns the gene ALB and malnutrition.