The ataxia coefficient, which is usually increased in HD53 was significantly decreased in contralateral forelimb in the CDNF-group (two-way RM ANOVA treatment × time interaction f8,102 = 2.002, p = 0.053; treatment effect f1,102 = 0.055, p = 0.814; time effect f8,102 = 0.939, p = 0.487). Here, CDNF is linked to cerebellar ataxia.