NR3C1 and major depressive disorder: These results of pharmacogenetics were observed for several polymorphisms of FKBP5 gene (which encodes a chaperon protein to GR) associated with clinical response in European Caucasian MDD patients to various antidepressant treatments, including selective serotonin reuptake inhibitors (SSRI), tricyclic antidepressant (TCA), and mirtazapine (drug targeting serotonergic and noradrenergic receptors)12.