Additionally, patients whose tumors acquired CDKN2A deletions had shorter time to progression and shorter time to subsequent surgery compared to patients with conserved CDKN2A deletions on primary and recurrent tumor samples (median time to progression: 5.5 versus 41.0 months (p = 0.009); median time to next surgery: 17.0 versus 41.0 months (p = 0.043), Fig. 3). Here, CDKN2A is linked to neoplasm.