The mechanisms of AKI induced by SARS-CoV-2 also involve hemodynamic factors, direct cellular injury caused by SARS-CoV-2 invasion through ACE2 or the cytokine storm induced by SARS-CoV-2, because the SARS-CoV-2 could not be detected in the postmortem autopsy or in the graft of renal transplantation patients when using RNA in-situ hybridization or by immunochemistry for nucleocapsid [47,48,49]. Here, ACE2 is linked to acute kidney injury.