Other putative stroke biomarkers related to ischemic stroke are brain damage proteins such as S100 calcium-binding protein B (s100b), neuron-specific enolase (NSE), light chain of neurofilament (NFL), tau, glial fibrillary acidic protein (GFAP), ubiquitin carboxy-terminal hydrolase L1 (UCHL-1), myelin basic protein (MBP), and brain-derived neurotrophic factor (BDNF) [183]. The gene discussed is NEFL; the disease is ischemic stroke.