At our analysis, out of the 96 downregulated miRNAs in ECD patients, 42 miRNAs are predicated to be involved in the regulation of the mTOR pathway (Table S3), suggesting that these miRNAs may contribute to the upregulation of this pathway, specifically miRNAs-15a-5p, 15b-5p, 107, and 21-5p and the let-7 family miRNAs that were validated by qRT-PCR. The gene discussed is MTOR; the disease is familial atrioventricular septal defect.