ITGAM and infection: The higher levels of CD11c+ dendritic cells and CD11b+ myeloid innate immune cells (eosinophils, monocytes, neutrophils) in the classical LAIV groups than those in the LAIV+4M2e groups, without significant differences in virological and clinical outcomes of the infection between study groups further support the hypothesis on the dual roles of innate immune cells in the respiratory tract in protection and in causing inflammatory disease [41].