CD8A and Crouzon syndrome-acanthosis nigricans syndrome: Analyses of the prognosis associations of FAP intensity in CD8a density-defined subgroups and of CD8a density in FAP intensity-defined subgroups showed similar results as in the U-CAN cohort, with significantly good prognosis associations of FAP intensity in the CD8a density-high group (Figure 3; p = 0.034; Log-rank test) and of CD8a density in the FAP intensity high-group (Figure 3; p = 0.042; Log-rank test).