AMH and polycystic ovary syndrome: Although overproduction of AMH is central to our understanding of the pathophysiology of PCOS, we propose a novel and complementary hypothesis that considers PCOS as an adverse psychological condition which develops in women at the onset of puberty and throughout adolescence as a consequence of stress, mood problems and low self-esteem, together with metabolic disturbances arising from eating disorders, which constitute a secondary confounder (Figure 1).