Further research on pancreatic cells from T1D patients linked the expression of miR-23a-3p, miR-23b-3p, and miR-149-5p with that of proapoptotic Bcl-2 proteins and consequent human β cell apoptosis [56], while autoreactive CD8+ T cells from patients with T1D showed evidence of repression of pro-apoptotic pathways via increased expression of miR-23b, miR-98, and miR-590-5p [57]. The gene discussed is BCL2; the disease is type 1 diabetes mellitus.