In contrast, BEMPEG treatment induced the expansion of CD25+ Foxp3− effector CD4+ T cells (Figure 2C,D), resulting in a 10‐fold increase in the ratio of CD4+ effector to CD4+ regulatory T‐cell fractions (% of live cells) in the lungs of K7M2‐WT tumor‐bearing mice (1.1 ± 0.2 for BEMPEG vs 0.1 ± 0.0 in the vehicle group; Figure 2E). Here, CD4 is linked to neoplasm.