In addition to APOE variants and rs646776, ABI3 variant rs28394864 was also associated with cardiovascular traits, such as hypertension (p = 1.60 x 10−13), ischemic heart disease (p = 4.58 x 10−9), coronary atherosclerosis (p = 6.47 x 10−10), and angina (p = 6.51 x 10−9). The gene discussed is APOE; the disease is hypertensive disorder.