The top 2 dmCpGs associated with maternal GDM were cg03566881, located within the body of the leucine-rich repeat-containing G-protein coupled receptor 6 (LGR6) gene (Fig 1D), and cg16536918, located within 200 bp of the transcription start site (TSS) of the arginine vasopressin (AVP) gene (Table 3). This evidence concerns the gene GPR6 and gestational diabetes.