DMRs within Pleckstrin Homology Domain Containing B1 (PLEKHB1) and Zinc Finger MYND-Type Containing 8 (ZMYND8) were associated with GDM, 1-h PG, and 2-h PG levels, while DMRs within the Bromodomain Containing 2 (BRD2) and TMEM210 genes were associated with both 1-h and 2-h PG levels; 26 DMRs were associated with both GDM and 1-h PG levels, including Thymocyte Selection Associated Family Member 2 (THEMIS2), 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (PLCH1), AVP, spondin 1 (SPON1), and oxytocin (OXT) genes (Table P in S1 Data, Fig 2B). This evidence concerns the gene PLEKHB1 and gestational diabetes.