LGR6 and gestational diabetes: The top 2 dmCpGs associated with maternal GDM were cg03566881, located within the body of the leucine-rich repeat-containing G-protein coupled receptor 6 (LGR6) gene (Fig 1D), and cg16536918, located within 200 bp of the transcription start site (TSS) of the arginine vasopressin (AVP) gene (Table 3).