CD177 and gestational diabetes: In addition, to adjust for the bias of multiple CpGs per gene, the GDM-associated dmCpGs were also inputted into methylglm function from the methylGSA package in R. MethylGSA analysis showed similar pathways enriched, with the GDM-associated dmCpGs showing enrichment for the GO terms cell surface receptor signalling pathway (FDR = 0.00082) and cytosol (FDR = 0.00362), while the 1-h PG-associated dmCpGs were enriched for the GO terms nuclear part (FDR = 4.91 × 10−10) and nucleoplasm (FDR = 1.14 × 10−9) (Table K in S1 Data).