When looking at the pneumotox.com (last access July 09th, 2020), a standard reference for ILD, the statement “pneumonitis/ILD, including acute and severe form (may occasion an ARDS picture),” is reported for palbociclib and abemaciclib, whereas for ribociclib, a general reference to the FDA warning on CDK4/6 inhibitors as a class is mentioned. This evidence concerns the gene CDK4 and acute respiratory distress syndrome.