APOE and Senile plaques: The positivity of Lewy pathology was significantly associated with age (male: positive cases, mean age at death = 81.1 ± 9.5 years; negative cases, 77.9 ± 11.8 years; female: positive cases, 86.4 ± 8.5 years; negative cases, 82.3 ± 11.0 years; p < 0.05) and higher pathological stages of neurofibrillary tangles (p < 0.0001) or senile plaques (p < 0.05), but not with sex, APOE status, or stages of argyrophilic grains or pTDP-43 (data not shown).