The other genes, including XRCC346 in the DSB pathway, TP5356 and MDM257 in the p53 pathway, AKT158 in the PI3K/PTEN/AKT pathway, SMAD359 in the TGF-β pathway, and MTHFR60 involved in folate metabolism, were also found in association with ORR, OS, or PFS in NSCLC patients using platinum-based regimen. The gene discussed is TGFB1; the disease is non-small cell lung carcinoma.