INS and diabetes mellitus: Negative regulation of apoptotic process, inflammatory response (GO:0006954), positive regulation of cell proliferation (GO:0008284), glucose homeostasis (GO:0042593) and glucose transport (GO:0015758) were found to be related with at least one of the KEGG pathways such as PI3K-Akt signaling pathway (hsa04151), TNF signaling pathway (hsa04668), insulin resistance (hsa04931), insulin signaling pathway (hsa04910), FoxO signaling pathway (hsa04068), adipocytokine signaling pathway (hsa04920), AMPK signaling pathway (hsa04152) and type 2 diabetes mellitus (hsa04930).