The data show that plantain mainly regulates pathways in cancer, HIF-1 signaling pathway, IL-17 signaling pathway, Chagas disease (American trypanosomiasis), and relaxin signaling pathway to treat gout (Figure 5(c)) and mainly regulates pathways in cancer, apoptosis, hepatitis B, IL-17 signaling pathway, and toxoplasmosis (Figure 5(d)) to treat hyperuricemia. Here, HIF1A is linked to Chagas disease.