In T2DM patients, circulating omentin-1 was positively associated with sex; HDL-C; apoA; NLR; urinary ACR; and prevalence of prior fragility fractures, DN, and DR, and it was negatively associated with TG, lymphocyte count, Hb, TBIL, DBIL, GGT, UA, OSTA, and BMD at different skeletal sites and corresponding T scores (P < 0.01 or P < 0.05; Table 2 and Figure 2). The gene discussed is GSTM1; the disease is liver dysplastic nodule.