They also were significantly older; had a higher level of urinary ACR; had a prevalence of DN; had lower Hb, TBIL, IBIL, GGT, and eGFR compared with individuals with normal BMD; and had a higher prevalence of PAD than individuals with osteopenia (P < 0.01 or P < 0.05; Table 1). This evidence concerns the gene GSTM1 and peripheral arterial disease.