TNF and autosomal dominant cerebellar ataxia: Differences were found in the levels of cytokines (IL1β, IL6, TNF-a, and TGF-β), lipid inflammatory mediators (LTB4 and PGE2), and modulators of vascular remodeling (MMP9 and TIMP1) between SCA individuals in steady- and crisis-state, permitting the characterization of these two groups using these parameters [13].