The PSA glycoforms from aggressive PCa patients showed two groups of N-glycan patterns in the UB fraction (α2,3-SA glycoforms) different from the ones obtained for the standard PSA; group 1 with FA2G2S2 (α2,3/α2,3) and group 2 with A2G1GalNAc1S1 (α2,3) as the major PSA glycoforms (Table 4). Here, KLK3 is linked to posterior cortical atrophy.