Thus, the β4GALNT4 upregulation in PCa tissues could explain the formation of the LacdiNAc group in FA2G1GalNAc1S2 (α2,6/α2,3) isomers, FA2G1GalNAc1S1 (α2,6) and A2G1GalNAc1S1 (α2,3) PSA glycoforms. Here, B4GALNT4 is linked to posterior cortical atrophy.