Of note, levels of total cholesterol, LDL-c and HDL-c were also higher in those without SCA (Table 1), whereas leukocyte count, circulating levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), triglycerides and CRP were higher among SCA patients who were not undertaking hydroxyurea therapy (Table 1). This evidence concerns the gene CRP and autosomal dominant cerebellar ataxia.