Hence hsa_circRNA_100380 (DCAF6), hsa_circRNA_101232 (ZDHHC20), hsa_circRNA_102893 (CLK1) and hsa_circRNA_103740 (SCLT1) were confirmed to be down regulated in GDM, whereas hsa_circRNA_102736 (XPO1) was up regulated (Fig. S2). This evidence concerns the gene CLK1 and gestational diabetes.