CSF2 and tuberculosis: To gain insight into the changes in gene expression caused by GM-CSF blockade during M. tuberculosis infection, we tested our previously reported blood modular TB signature, which distinguishes TB patients from healthy controls35 and is recapitulated in TB-susceptible strains of mice16, on our blood RNA-Seq data from infected and uninfected αGM-CSF versus Ctrl Ab treated mice (Supplementary Data 3 and Fig. 2a).