This is in keeping with cellular deconvolution analysis36 showing an increase in the percentage of myeloid and neutrophil fractions in the blood from infected αGM-CSF compared to infected Ctrl Ab treated mice (Supplementary Fig. 3a), which was reflected by increased expression of neutrophil, monocyte and macrophage-associated genes induced by GM-CSF blockade during infection (Supplementary Data 2 and Supplementary Fig. 3b–d), and was similar to our previous report of the blood signature in human TB and TB-susceptible mice16. This evidence concerns the gene CSF2 and tuberculosis.