TNNT2 and familial dilated cardiomyopathy: The introduction of the dilated cardiomyopathy (DCM)-causing TNNT2 mutation ΔK210 in reconstituted thin filaments led to decreased Ca2+-sensitivity when using WT and ΔK210 cTnT in a 50:50 ratio, whereas it resulted in increased Ca2+-sensitivity when using 100% ΔK210 [40].