The authors discovered that younger (< 65 years old) APOE4− AD patients performed worse on executive function tasks compared to younger APOE4+ AD patients, while intermediate (65–74 year-old) APOE3/4 AD patients performed worse on visuospatial tasks compared to intermediate APOE4/4 AD patients, and older (≥ 75 years old) APOE4/4 AD patients performed worse on verbal memory compared to older APOE4− AD patients [58]. Here, APOE is linked to Alzheimer disease.