Two comprehensive genomic analyses including the TCGA dataset identified alterations in CTNNB1, TP53, CDKN2A, RB1 and MEN1—genes that had previously been reported as mutated in ACC—as well as in ZNRF3, DAXX, TERT and MED12 [8, 16]. Here, CTNNB1 is linked to adrenal cortex carcinoma.