Several biomarkers have been suggested to identify laboratory parameters that could allow to detect early individuals that present high risk of developing severe COVID: lymphopenia, leukopenia, prolonged prothrombin time, elevated lactate dehydrogenase (LDH), elevated transaminases (AST and ALT), increased protein C-reactive (CRP) and procalcitonin (PCT), elevated levels of IL-6, CRP, LDH and D-Dimer [29]. This evidence concerns the gene CRP and lymphopenia.