CD248 and central nervous system cancer: Notably, only the expression of CD248, was increased in GBMwt_lo tumors compared to IDHmut gliomas (Figure 4L), which correlated with the higher CD248 score measured by IHC (Figure 4D and Figure S5), suggesting a direct correlation between the absence of IDH mutations and the increase in tumor pericytes, as we have recently described [11].