Among the IDHwt GBMs, we observed a heterogeneous profile: some of the tumors showed a low content of CD45+ cells, with a very similar percentage of immune cells to the one measured in IDHmut tumors (either LGGs or GBMs), whereas in others there was a strong presence of leukocytes, reaching 50% of the tumor content in some cases (Figure 1D). Here, PTPRC is linked to neoplasm.