Fig 1 shows immunohistochemistry images derived from renal biopsy specimens. No statistically significant difference was found when patients with and without TMA were compared for number of CD68 positive glomerular (4.3 vs. 2.25, p = 0.12) or interstitial (25.4 vs. 18.3, p = 0.25) cells. The comparison between patients progressing or not to CKD-KRT did not yield significant differences for glomerular cells labeled positive for CD68 (3.35 vs. 2.24, p = 0.38), but significantly more CD68 interstitial cells were seen in individuals progressing to CKD-KRT (32.5 vs. 15.6, p<0.0001) (Table 4). This evidence concerns the gene CD68 and chronic kidney disease.