Our results showed that Jinhua Qinggan Granule, Lianhua Qingwen Granule, Xuebijing Injection, Qingfei Paidu Decoction, HuaShi BaiDu Formula, and XuanFeiBaiDu Granule could decrease IL-6 through several compounds, such as quercetin, ursolic acid, luteolin, and rutin, showing a therapeutic effect on COVID-19 treatment (Figure 12). This evidence concerns the gene IL6 and COVID-19.