Methylation analysis of 147 bp containing nine CpG sites in the evaluated region of the 5′UTR of CYFIP1 showed significant consistent DNA hypermethylation in the cancer patients compared with healthy controls (Fig. 2), while analysis of 124 bp containing two CpG sites in intron 1 of CDCP1 showed significant hypomethylation in cancer patients. This evidence concerns the gene CYFIP1 and cancer.