Meanwhile, higher level of CD8+PD-1+CD161+ T cells in non-tumor adjacent tissues indicates the favorable prognosis after resection (RFS, high vs. low = 54.9 months vs. 24.3 months, P = 0.0062; OS, high vs. low = 66.1 months vs. 37.5 months, P = 0.0325) (Fig. 4c). This evidence concerns the gene CD8A and neoplasm.