The inducers used in this study represent the broad range of different stimuli that the NLRP3 inflammasome can respond to ATP is a DAMP involved in autoinflammatory diseases that arise during sterile inflammatory conditions, including CAPS and FMF, conditions involving both IL-1β and IL-18 [49, 50]. The gene discussed is NLRP3; the disease is cryopyrin-associated periodic syndrome.