ST6GAL1 and ovarian cancer: In a 2018 study of ovarian cancer using ST6GAL1 mRNA levels from a public database (n = 517), along with the analysis of ST6GAL1 protein levels of 204 tumour samples, Wichert et al.140 found that high ST6GAL1 mRNA levels correlated with lymphovascular invasion and shorter survival, while high levels of ST6GAL1 protein expression correlated with advanced stage, metastasis and shorter recurrence-free intervals, indicating that ST6GAL1 expression levels could help identify the risk of chemoresistance and metastatic relapse.140