CDKN2A, TP53, TTN, KCNJ18, and KRAS had the highest CP values among the patients with PAAD, and survival and recurrence rates were significantly different between the patients harboring mutations in these candidate genes and those harboring mutations in other genes (p = 2.39E−03, p = 8.47E−04, respectively). This evidence concerns the gene TTN and pancreatic adenocarcinoma.