TM4SF1 and neoplasm: We found that the Clara cell progenitor marker SCGB3A2 [30, 31] (LogFoldChange = 16.21089, adjusted p value = 9.088149e−93) and alveolar epithelial progenitor (AEP) marker TM4SF1 [32] (LogFoldChange = 0.9938625, adjusted p value = 1.553989e−104) were upregulated in tumor cells (Fig. 4d, e, Supplmentary Fig. S9).