Knocking down ELF3 expression attenuates activation of NF-κB pathway genes in two LUAD cell lines A549 (KRAS mutation) and NCI-H1975 (EGFR mutation L858R), supporting the conclusion that inflammatory cytokines (e.g. IL1B) can regulate tumor cell proliferation and anti-apoptosis through ELF3 action. This evidence concerns the gene NFKB1 and neoplasm.