When comparing the epidemiological results with the brain autopsies results, it is important to note that FTD is a clinical term; the neuropathological counterpart is Frontotemporal Lobar Degeneration (FTLD) with different causes: TDP-43 proteinopathy, tauopathy or the rarer FTLD (i.e. FUS). The gene discussed is TARDBP; the disease is tauopathy.